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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
G6PD
All Species:
47.27
Human Site:
S486
Identified Species:
74.29
UniProt:
P11413
Number Species:
14
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P11413
NP_000393.4
515
59257
S486
P
I
P
Y
I
Y
G
S
R
G
P
T
E
A
D
Chimpanzee
Pan troglodytes
XP_001146640
398
44780
N370
E
A
G
R
E
Q
N
N
Q
V
V
L
G
F
V
Rhesus Macaque
Macaca mulatta
XP_001095273
515
59249
S486
P
I
P
Y
L
Y
G
S
R
G
P
M
E
A
D
Dog
Lupus familis
XP_538209
545
62703
S516
P
I
P
Y
V
Y
G
S
R
G
P
P
E
A
D
Cat
Felis silvestris
Mouse
Mus musculus
Q00612
515
59244
S486
P
I
P
Y
V
Y
G
S
R
G
P
T
E
A
D
Rat
Rattus norvegicus
P05370
515
59357
S486
P
I
P
Y
V
Y
G
S
R
G
P
T
E
A
D
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505636
515
59203
S486
P
I
P
Y
R
Y
G
S
R
G
P
A
E
A
D
Chicken
Gallus gallus
Frog
Xenopus laevis
NP_001080019
518
59674
S489
P
H
P
Y
K
Y
G
S
R
G
P
A
E
S
D
Zebra Danio
Brachydanio rerio
XP_699168
523
59677
S494
P
I
K
Y
K
Y
G
S
R
G
P
A
E
A
D
Tiger Blowfish
Takifugu rubipres
P54996
530
60451
S501
P
I
P
Y
K
Y
G
S
R
G
P
A
E
A
D
Fruit Fly
Dros. melanogaster
P12646
524
60412
S491
P
I
T
Y
Q
Y
G
S
R
G
P
K
E
A
D
Honey Bee
Apis mellifera
XP_001121185
518
60246
S454
I
L
D
V
F
C
G
S
Q
M
H
F
V
R
N
Nematode Worm
Caenorhab. elegans
Q27464
522
60197
S494
P
V
Q
Y
K
F
G
S
R
G
P
T
E
G
D
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9FJI5
515
59098
S487
S
I
P
Y
K
P
G
S
R
G
P
K
E
A
D
Baker's Yeast
Sacchar. cerevisiae
P11412
505
57503
S469
P
E
I
Y
P
Y
G
S
R
G
P
K
G
L
K
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
67.9
99
87.8
N.A.
93.7
93.7
N.A.
90.2
N.A.
77.2
75.3
74.3
61.2
63.7
58.8
N.A.
Protein Similarity:
100
69.1
99.6
91.5
N.A.
97
96.6
N.A.
96.1
N.A.
89.7
85.8
82.6
74
76.8
74.9
N.A.
P-Site Identity:
100
0
86.6
86.6
N.A.
93.3
93.3
N.A.
86.6
N.A.
73.3
80
86.6
80
13.3
66.6
N.A.
P-Site Similarity:
100
13.3
93.3
93.3
N.A.
100
100
N.A.
86.6
N.A.
80
80
86.6
80
33.3
80
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
52.2
46.4
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
68.5
63.8
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
73.3
53.3
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
7
0
0
0
0
0
0
0
0
0
27
0
67
0
% A
% Cys:
0
0
0
0
0
7
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
0
0
80
% D
% Glu:
7
7
0
0
7
0
0
0
0
0
0
0
80
0
0
% E
% Phe:
0
0
0
0
7
7
0
0
0
0
0
7
0
7
0
% F
% Gly:
0
0
7
0
0
0
94
0
0
87
0
0
14
7
0
% G
% His:
0
7
0
0
0
0
0
0
0
0
7
0
0
0
0
% H
% Ile:
7
67
7
0
7
0
0
0
0
0
0
0
0
0
0
% I
% Lys:
0
0
7
0
34
0
0
0
0
0
0
20
0
0
7
% K
% Leu:
0
7
0
0
7
0
0
0
0
0
0
7
0
7
0
% L
% Met:
0
0
0
0
0
0
0
0
0
7
0
7
0
0
0
% M
% Asn:
0
0
0
0
0
0
7
7
0
0
0
0
0
0
7
% N
% Pro:
80
0
60
0
7
7
0
0
0
0
87
7
0
0
0
% P
% Gln:
0
0
7
0
7
7
0
0
14
0
0
0
0
0
0
% Q
% Arg:
0
0
0
7
7
0
0
0
87
0
0
0
0
7
0
% R
% Ser:
7
0
0
0
0
0
0
94
0
0
0
0
0
7
0
% S
% Thr:
0
0
7
0
0
0
0
0
0
0
0
27
0
0
0
% T
% Val:
0
7
0
7
20
0
0
0
0
7
7
0
7
0
7
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
87
0
74
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _